tag:blogger.com,1999:blog-17248466996909196852024-03-13T11:37:26.010-07:00MISHA'S JOURNEYmy journey till nowmisha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.comBlogger56125tag:blogger.com,1999:blog-1724846699690919685.post-22701062857348708782012-11-01T22:18:00.001-07:002012-11-01T22:18:03.776-07:00last months after a long pause ,I will try to update a bit of what happened in the past weeks or more like 2 months<br />
<br />
In september we where supposed to go to Holland and Belgium for Misha her next ABR training .<br />
So sadly we missed our next training and for the next 6 months we have to keep on doing the same once's we have been doing .<br />
at the end of August Misha also had 5 day's of reabilitacion in oaxaca city in the CRIT(teleton) ,<br />
5 long day's ,weak up at 6 am going to the center not getting back till the afternoon .<br />
<br />
we had 2 weeks in between oaxaca and our travels, Misha whas doing great till the night we had to travel,the airlines are not to flexible even with sickness we lost our tickets and hotel :(<br />
<br />
we where not able to fly because misha had a bad bronchitis ,she had to go on asma medicacion ,<br />
2 x a day nebuelizations to help the swelling of the bronchus to go down ,so she had to take antibiotic's to help speed up the proses of the infection.<br />
<br />
when ever Misha takes antibiotic's she has problems with her stomach for the next 6 weeks ,have to find a natural type of antibiotic's ,so any one an idea the are more then welcome<br />
<br />
so little sleep for me taking care of her at night trying to do her therapy in the day in between feedings getting her to drink enough water <br />
<br />
Misha luckily got better in 2 weeks and then we had to go to the reabilitacion center in oaxaca city 15 16 and 17 of October ,there they put Misha on a special machine ,they put a special jacket on the child it puts in air and it shakes ,it helped a lot to clear up her bronchus ,she will has 2 more treatments with this machine in December <br />
<br />
also one day while eating breakfast she was having fun and she started to laugh ,but laughing with sound ,still waiting for it to happen again ,it was the greatest day ever :).<br />
<br />
she has been very tired lately i think she must be growing ,hope so .<br />
<br />
Misha is having some weight problems she in not gaining any weight ,she has lots ,must be having been sick so now we are trying to help her gain some ,hope so .<br />
right now Misha is sleeping so that means i need to sleep to ,goodnight <br />
misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-40027709907789322652012-08-07T16:43:00.001-07:002012-08-07T16:43:21.530-07:00Being sickSaterday misha started feeling bad ,by sunday fever even with a paracetamol de fever kept up ,going up and down ,luckly we where able to contact her docter and on a sunday,he whas not in town but indicated what to give her .<br />
Now she has oral antibiotics for one week and for 3 days she needs a injection of antibiotics ,also taking claritin and something for the pain and fever. And a asma medication and vapor baths<br />
Luckly today she is feeling better ,hungry again and wanting to drink.<br />
You can see very well when misha feels sick then she turns her eyes up ,now she looks strait forward again.<br />
Today we got smiles again A happy face ,she even cryed to get food<br />
Misha got me sick to so we are nicly sitting togetter and cudeling ,the way we love :)misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-45085135103747496542012-08-01T08:17:00.001-07:002012-08-01T08:17:18.191-07:00little pool<div class="separator" style="clear: both; text-align: center;">
<a href="http://2.bp.blogspot.com/-CsaptjFELXA/UBlA4pVJ1rI/AAAAAAAAALk/pAj0VGYnGq0/s1600/misha+uit+bad.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="http://2.bp.blogspot.com/-CsaptjFELXA/UBlA4pVJ1rI/AAAAAAAAALk/pAj0VGYnGq0/s320/misha+uit+bad.jpg" width="320" /></a></div>
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="http://4.bp.blogspot.com/-OBR-_th9sbk/UBlA734Kc9I/AAAAAAAAALs/ADiphY8sHPg/s1600/missy+uit+bad.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="http://4.bp.blogspot.com/-OBR-_th9sbk/UBlA734Kc9I/AAAAAAAAALs/ADiphY8sHPg/s320/missy+uit+bad.jpg" width="320" /></a></div>
misha love the water ,she love to be in her little plastic pool ,that is where she takes her shower ,<br />
she relaxes and becomes all smilly and happy<br />
she also likes the big pool and she knows how to floot ,you just need to hold her head<br />
bit sadly it looks like she got an blader infection the last time we went ,so now we are not sure to try again<br />
i husts to see misha in so much pain misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-84709543447731626712012-07-14T22:08:00.001-07:002012-07-14T22:36:53.931-07:00SOME PHOTOS<div class="separator" style="clear: both; text-align: center;">
<a href="http://4.bp.blogspot.com/-WDuvlVGkPfM/UAJOTkORS1I/AAAAAAAAALI/el7cE2zYGvU/s1600/SIESTA+WITH+TIGRE.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="http://4.bp.blogspot.com/-WDuvlVGkPfM/UAJOTkORS1I/AAAAAAAAALI/el7cE2zYGvU/s320/SIESTA+WITH+TIGRE.jpg" width="320" /></a></div>
<br />
<div class="separator" style="clear: both; text-align: center;">
<a href="http://4.bp.blogspot.com/-bYjbvne8M7w/UAJO9sGHcFI/AAAAAAAAALU/8N9Z4WXEKV4/s1600/MY+FAMILY.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="http://4.bp.blogspot.com/-bYjbvne8M7w/UAJO9sGHcFI/AAAAAAAAALU/8N9Z4WXEKV4/s320/MY+FAMILY.jpg" width="320" /></a></div>
<div class="separator" style="clear: both; text-align: center;">
MISHA HAS BEEN SLEEPING A LOT DE PAST COUPLE OF DAY </div>
<div class="separator" style="clear: both; text-align: center;">
SHE LOVES TO SLEEP WITH THE CATS AND THE CATS REALLY LOVE HER </div>
<div class="separator" style="clear: both; text-align: center;">
THEY ALWAYS COME TO SEE HOW SHE IS DOING AND THEY LOVE TO SLEEP NEXT TO HER </div>
<div class="separator" style="clear: both; text-align: center;">
THEY CAN FEEL SHE IS SPECIAL.</div>
<div class="separator" style="clear: both; text-align: center;">
IT HAS BEEN A WHILE SINDS WE REPORTED ,BUT THAT IS BECAUSE WE DID NOT HAVE MUCH TO REPORT WE BOTH HAVE BEEN EXTREEMLY TIRED ,WE ALSO DID NOT GET AS MUCH ABR HOURS AS WE LIKE </div>
<div class="separator" style="clear: both; text-align: center;">
BUT WE DO SEE MISHA IS MUCH STRONGER HER HEAD CONTROL IS GETTING BETTER </div>
<div class="separator" style="clear: both; text-align: center;">
WHEN SHE SITS ON MY LAP OR ON THE BED SHE NEEDS MUCH LESS SUPORT FROM ME </div>
<div class="separator" style="clear: both; text-align: center;">
THAT IS GREAT !!</div>
<div class="separator" style="clear: both; text-align: center;">
WE CAN NOT WAIT FOR THE DAY THAT MISHA SITS BY HER SELF </div>
<div class="separator" style="clear: both; text-align: center;">
THOSE ARE THE SPECIAL MOMENTS WHEN YOU SEE ALL WE HAVE DONE AND THE GREAT RESULTS WE HAVE MADE :)</div>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com1tag:blogger.com,1999:blog-1724846699690919685.post-52274999067828068312012-06-18T21:08:00.004-07:002012-06-18T21:08:45.500-07:00surviving huracain charlottafrijday evening huracain charlotta entered in to puerto escondido ,i am very happy to say misha slept tru the hole ordeal when she woke up it whas just a normal day for her.<br />
it was very scary ,in 1997 huracain paulina also came strait for puerto ,a bigger huracain ,but charlotta whas much more scarry the winds sceamed ,all kinds of debrie flying tru the sky ,it was dark and no lights .<br />
maybe better sinds we could not see all that happend around us !<br />
<br />
the doors to my house almost blew inside had to build in between my 2 doors a cloth wall ,our 4 dogs and 14 cats where all scared and we had to lock them inside the down part of the house and we 3 ( misha me and katia )where upstairs,we where very lucky the man that works here he helpt us a lot getting the water of our patio and making sure everything whas secure ,we did make preperacions in the day to secure all lose things got locked up so nothing culd fly or drift away.<br />
<br />
the water in the street could go no where it became a river with palm leaves ,matresses ,tables trash ,glass ect.,there came no help from the city ,we had to take the trash from the street so the water could go in the rain drain and go to the beach .<br />
<br />
today we had some sun so everything could dry a bit ,but this evening the rain started again <br />
and it looks like the haevy rains and winds can come back we will now in the next 24 till 48 hrs<br />
the remances of charlotta died but where she died of there are new flares of rain and not sure where they will be heading hope they go in the ocean and do not come back south<br />
lots of people here in town lots all there belonings there roofs blew of there homes and the water came in ,also lots of the restaurants on zicatela beach have lots of damage .<br />
we do hope for every ones sacke the rains stay in the ocean and leave us alone,pleaseeee<br />misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-58261970524902968862012-06-12T23:15:00.001-07:002012-06-12T23:15:21.097-07:00sleepy headmisha can be a sleepy head ,the past 2 days she has slept in the day time,the hole day.<br />
but then at night time she becomes a naughty girl and does not let her mommy sleep.<br />
she keept on waking me up every 2 hours by little sreams ,hope tonight she will sleep.<br />
<br />
now it is one A.M. and she is still on the move in her bed ,some screams ,kicking and hard she wants to be in her mommy's arm's<br />
she got me ,i went to get her she is now with me in bed ,she is starting to close her eyes .<br />
she is such a love ,she give so mucho love and loves to receive hugs and kisses .<br />
<br />misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-24388388498691314972012-06-03T22:58:00.003-07:002012-06-03T22:58:54.162-07:00time fly's byit has been a while sinds we posted but time seems to fly by ,your always bussy<br />
doing our ABR training ,eating ,bathing ,drinking and it is already night again<br />
so today we said ok we take a day to just be together and just hug lay in the pool and hug some more ,go for a walk by the beach ,we never get time for the fun things,it is just misha her mom(me) and katia <br />
we are always in a hurry to get the most therapy done (what is not always easy),to make sure misha has eaten anough ,did she drink anough,she does not like to drink,she is drinking this past week much better<br />
today she ate and drank very well ,misha is trying different foods ,and to our good pleasure it is going all very well.<br />
in september we will have our next ABR training <br />
going to sleep right now ,sinds misha is a sleep :)<br />misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-45763479272792718202012-05-12T21:54:00.002-07:002012-05-12T21:54:45.936-07:00<div class="separator" style="clear: both; text-align: center;">
<a href="http://4.bp.blogspot.com/-qJyaJQzIWtY/T68-biBBJ7I/AAAAAAAAAKA/zNiMenz1gPY/s1600/misha+and+regina.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" src="http://4.bp.blogspot.com/-qJyaJQzIWtY/T68-biBBJ7I/AAAAAAAAAKA/zNiMenz1gPY/s1600/misha+and+regina.jpg" /></a></div>
with my sweeth nice regina who come to visit me ,we love eachothermisha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-21052091077986313262012-05-12T21:42:00.001-07:002012-05-12T21:42:22.415-07:00little angelwe have done for the first 3 years fisical reabilitacion and really did not see many changes .<br />
at one month she was able to hold her little head up and hold her bottle ,then she started anti epileptic mediceins and she only slept til she whas 8 months old!!!<br />
i have taken her off almost al the anti epileptic meds and she is doing so much better<br />
the neurologist does not like my disicion <br />
<br />
after that misha never gained head control, arm movements ,sitting she never even got to the first milestones<br />
.<br />
we did the glen domann book and misha showed more reactions but her body whas not strong ,her body whas colapsed ,then we started to do ABR(adanved biomecanical reabititacion) and to my opinion rater fast i shaw changes coming ,misha never had a neck her head kind of rested on her sholders and in 2 months i saw changes coming ,now over a year of doing ABR we see changes and for a little girl like misha they are a lot ,all the docters we have seen either told us she could never do any thing just kind of keep her healty and move her a bit .<br />
we are very happy to have started ABR and have her on g-therapy,now we see changes they said misha would never make !!<br />
i never gave up on her i always said no she will she will <br />
and i still say she will ,it is just a lot of work and many hours ,she is an angel and worth all the work ,i will never give up !!!some days are very hard one gets tired and some times i feel sick but misha comes first so we go on<br />
i want to see misha sit by her self and hold up her head <br />
then we go and visit all the people who said no she never will ,we are working to that and we will do it <br />
she is my angel and she works very hard in getting better and being the best she can be<br />misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-41371728336311951152012-05-11T22:00:00.001-07:002012-05-11T22:00:54.709-07:00<div class="separator" style="clear: both; text-align: center;">
<a href="http://1.bp.blogspot.com/-9aCjPoyKeLU/T63t_QdGUlI/AAAAAAAAAJ0/Nup6nHTebNE/s1600/DSC01232.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="http://1.bp.blogspot.com/-9aCjPoyKeLU/T63t_QdGUlI/AAAAAAAAAJ0/Nup6nHTebNE/s320/DSC01232.JPG" width="320" /></a></div>
<br />
working on opening up the sholder,in a short peroid of time we see the movement opening up <br />
misha loves to sleep while i work on her<br />misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-90825923769497467462012-05-11T21:55:00.002-07:002012-05-11T21:55:42.902-07:0035 degrees of heatwe have been out of it ,trying to keep cool it is 35 degrees and feels like 41 ,you do not need to move to sweath ,even with a fan on it is still to hot ,also the heat has got us on a rollercoaster ride with colds ,most poeple will go how!! a cold comes with cold weather but no here you get it when it is to hot and the fan spinning directly on you<br />
do hope for rain soon ,then it will cool of some.<br />
misha does not like the heath ,she loves it to go in her little pool and just lay there she get really relaxed and full of smiles.<br />
so doing our ABR hours with this heat has been hard.<br />
but progres is coming we see misha getting stronger bit by bit :)misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-73744261502846416092012-05-02T22:17:00.004-07:002012-05-02T22:17:40.729-07:00FAMILYfamily ,what suld you expect from you family ????<br />
that is a question that has been on my mind for a long time <br />
one feels they suld be there for you in the hard times and one hopes for there suport and help special for a special needs child <br />
one as a mom to a special needs child you give your live for your angel ,not thinking 2 X abouth it. <br />
it is very hard when the famlily of your special needs child do not feel the same way abouth your special needs child or do not show it ,do they come by for love or is it more a must ,do they hide the fact that there is a special needs child in there famliy???<br />
I have many questions ??????<br />
all I now is I take care of my little angel ,I love her she is special and any one who does not see that is blind ,misha is a most special child she is an angel walking this earth and she deserves respect .<br />
it makes me sometimes very sad ,and very happy to see lots of the other little angels with there familys ,and how they are happy proud and spend time with with there special needs child ,how they try to be part of there special lives and do there best to make there live the best it can be.<br />
I do hope one day misha her family will see how special she is and want to be part of her live .<br />
me as your mommy misha I love you you are my everything I miss you when i do not see you for 5 minutes ,I love you my little angel !!misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-72906969808296893712012-04-17T09:15:00.000-07:002012-04-17T09:15:55.686-07:00new cures on the way for nuerological diseases<span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Pubblicato ieri su PLoS ONE uno studio condotto da ricercatori dell'ISS che fa luce sul meccanismo alla base degli effetti del CNF1 sul cervello e apre nuovi scenari nella lotta alle malattie rare">today a facebook friend posted this webpage sounds very interesting</span><br />
<span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Pubblicato ieri su PLoS ONE uno studio condotto da ricercatori dell'ISS che fa luce sul meccanismo alla base degli effetti del CNF1 sul cervello e apre nuovi scenari nella lotta alle malattie rare">here the original webpage in italian and the translation is underneed</span><br />
<span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Pubblicato ieri su PLoS ONE uno studio condotto da ricercatori dell'ISS che fa luce sul meccanismo alla base degli effetti del CNF1 sul cervello e apre nuovi scenari nella lotta alle malattie rare"><a href="http://osservatoriomalattierare.it/sindrome-di-rett/1984-sindrome-di-rett-una-tossina-di-escherichia-coli-come-possibile-cura">http://osservatoriomalattierare.it/sindrome-di-rett/1984-sindrome-di-rett-una-tossina-di-escherichia-coli-come-possibile-cura</a>-</span><br />
<br />
<br />
<br />
<span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Pubblicato ieri su PLoS ONE uno studio condotto da ricercatori dell'ISS che fa luce sul meccanismo alla base degli effetti del CNF1 sul cervello e apre nuovi scenari nella lotta alle malattie rare">Published today in PLoS ONE study conducted by researchers at ISS that sheds light on the mechanism underlying the effects of CnF1 on the brain and opens new scenarios in the fight against rare diseases<br />
</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Si aprono nuovi possibili scenari nella lotta alla Sindrome di Rett, grave malattia del neurosviluppo per la quale non esiste a tutt'oggi una cura.">They open new scenarios in the fight with Rett syndrome, severe neurodevelopmental disease for which there is still no cure.<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="È di ieri infatti la pubblicazione sulla rivista PLoS ONE di uno studio, condotto dai ricercatori dei Dipartimenti del Farmaco e di Biologia Cellulare e Neuroscienze dell'Istituto Superiore di Sanità, in cui si evidenzia uno dei meccanismi alla base delle attività di una tossina prodotta dal">It is in fact yesterday's publication in the journal PLoS ONE study, conducted by researchers from the Departments of Medicine and Cell Biology and Neuroscience Institute of Health, which highlighted one of the mechanisms underlying the activity of a toxin produced by<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="batterio Escherichia coli (il CNF1) sulla plasticità del sistema nervoso.">bacterium Escherichia coli (the CnF1) on the plasticity of the nervous system.<br />
</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="“I risultati si sono rivelati incoraggianti – commenta il Presidente dell'ISS, professor Enrico Garaci – in quanto aprono la strada alla possibilità di un'applicazione terapeutica della tossina CNF1 nella sindrome di Rett ma anche in altre malattie rare con deficit cognitivi e motori.">"The results were encouraging - ISS said the President, Professor Henry Garaci - they open up the possibility of a therapeutic application of the toxin CnF1 in Rett syndrome but also in other rare diseases with cognitive and motor deficits.<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Gli studi più recenti hanno condotto alle prime dimostrazioni in vivo del ruolo di questa sostanza e hanno quindi una maggiore rilevanza translazionale”.">More recent studies have led to the first in vivo demonstration of the role of this drug and thus have a greater translational relevance. "<br />
</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Nello studio pubblicato oggi su PLoS ONE si dimostra come il trattamento con il CNF1 di astrociti (cellule gliali da sempre considerate “ancelle” dei neuroni ma il cui ruolo nella funzionalità cerebrale si va progressivamente rivalutando) sia in grado di favorire la crescita in vitro dei">In the study published today in PLoS ONE shows how the treatment with the CnF1 of astrocytes (glial cells has always been considered as "handmaids" of neurons but whose role in brain function is gradually revaluing) is able to promote the in vitro growth of</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="neuroni coltivati al loro fianco nonché la formazione di sinapsi (sinaptogenesi).">neurons cultured on their side and synapse formation (synaptogenesis).<br />
</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="L'azione a livello astrocitario del CNF1 costituisce una caratteristica importante di questa molecola proteica, poiché la rende un prezioso strumento nella messa a punto di terapie mirate non solo per la sindrome di Rett ma anche per tutte quelle caratterizzate da anomalie astrocitarie.">The action at the level of the astrocytic CnF1 constitutes an important feature of this protein molecule, for making it a valuable tool in the development of targeted therapies not only for the Rett syndrome but also for all those characterized by abnormal astrocyte.</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Come nel caso di altre sostanze prodotte da specie microbiche (si pensi ad esempio alla neurotossina botulinica, la cui applicazione spazia dalla cosmesi alla patologia muscolare e al trattamento delle patologie algiche), la tossina di Escherichia coli conferma dunque che l'azione a livello cellulare">As with other substances produced by microbial species (consider, for example, the botulinum neurotoxin, which ranges from cosmetics applied to the muscle pathology and treatment of diseases algiche), the toxin of Escherichia coli confirms that the action at the cellular level<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="di prodotti naturali quali le tossine di origine batterica può avere ricadute molto importanti in campo medico.">natural products such as toxins of bacterial origin can have very important implications in the medical field.<br />
</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="“Il proseguimento della ricerca – spiega la dottoressa Carla Fiorentini, coordinatrice del gruppo multidisciplinare in ISS che studia il CNF1 - prevede lo studio degli effetti di questa tossina su altri modelli animali, sia di patologie neurodegenerative, quali l'Alzheimer, sia di alterazioni del">"The continuation of the research - said Dr Carla Fiorentini, coordinator of the multidisciplinary group that studies the ISS CnF1 - includes the study of the effects of this toxin in other animal models, both of neurodegenerative disorders such as Alzheimer's, both of alterations<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="neurosviluppo, associate a disabilità intellettiva e/o motoria.">neurodevelopment, are associated with intellectual disability and / or motor.<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Obiettivo cruciale e finale dei nostri studi è ovviamente l'avvio della sperimentazione nell'uomo.">Crucial and final goal of our studies is obviously the start of the trial in humans.</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Quest'ultimo punto richiede la sintesi del CNF1 secondo le Good Manufacturing Practice e lo svolgimento delle varie procedure necessarie per la richiesta di autorizzazione di uno studio di fase I del prodotto da parte di Laboratori accreditati”.">The latter necessitates the synthesis of CnF1 according to Good Manufacturing Practice and carrying out the various procedures necessary for the request for authorization of a phase I study of the product by accredited laboratories. "<br />
</span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="Lo studio conferma il ruolo-chiave della tossina, già emerso in un lavoro pubblicato poche settimane fa su Neuropsychopharmacology: in questo caso i ricercatori ISS hanno dimostrato come in topi transgenici, modello per la Sindrome di Rett, la tossina riesca a combattere le alterazioni a">The study confirms the key role of the toxin, which emerged in a paper published a few weeks ago on Neuropsychopharmacology: in this case the ISS researchers have shown that in transgenic mice, a model for Rett syndrome, the toxin is able to fight the changes in<span class="Apple-converted-space"> </span></span><span style="-webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; background-color: whitesmoke; color: #333333; font-size-adjust: none; font-stretch: normal; font: 16px/normal arial, sans-serif; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px;" title="livello degli astrociti così come i problemi cognitivi ei deficit di coordinazione motoria tipici della patologia.">layer of astrocytes as well as cognitive problems and motor coordination deficits typical of the disease.</span>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-71582178569127617642012-04-08T08:33:00.003-07:002012-04-08T08:33:46.159-07:00misha her ABR report of 2011<div class="separator" style="clear: both; text-align: center;"><a href="http://2.bp.blogspot.com/-idua5glWaWM/T4GuozFdOhI/AAAAAAAAAIw/XXMk2P9e30M/s1600/abr+report0001.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="241" src="http://2.bp.blogspot.com/-idua5glWaWM/T4GuozFdOhI/AAAAAAAAAIw/XXMk2P9e30M/s320/abr+report0001.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://2.bp.blogspot.com/-ylC_bbzQ7fI/T4GvOqcipZI/AAAAAAAAAI4/D9KWF8JrN6k/s1600/abr+report0002.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="241" src="http://2.bp.blogspot.com/-ylC_bbzQ7fI/T4GvOqcipZI/AAAAAAAAAI4/D9KWF8JrN6k/s320/abr+report0002.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://2.bp.blogspot.com/-vlGEQOtW_dk/T4GvTAyBCzI/AAAAAAAAAJA/oiRCW5s6c4A/s1600/abr+report0003.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="275" src="http://2.bp.blogspot.com/-vlGEQOtW_dk/T4GvTAyBCzI/AAAAAAAAAJA/oiRCW5s6c4A/s320/abr+report0003.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://1.bp.blogspot.com/-C2ScqWUIy7Q/T4GvZG15K0I/AAAAAAAAAJI/pYhbvr7FVQs/s1600/abr+report0004.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="275" src="http://1.bp.blogspot.com/-C2ScqWUIy7Q/T4GvZG15K0I/AAAAAAAAAJI/pYhbvr7FVQs/s320/abr+report0004.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://4.bp.blogspot.com/-Ftc-a49S3_w/T4GvdMzqhjI/AAAAAAAAAJQ/isciJW7jve4/s1600/abr+report0005.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="252" src="http://4.bp.blogspot.com/-Ftc-a49S3_w/T4GvdMzqhjI/AAAAAAAAAJQ/isciJW7jve4/s320/abr+report0005.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://3.bp.blogspot.com/-J-TLKhDpEas/T4Gvhj5S3nI/AAAAAAAAAJY/uj9qIMcfmH8/s1600/abr+report0006.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="260" src="http://3.bp.blogspot.com/-J-TLKhDpEas/T4Gvhj5S3nI/AAAAAAAAAJY/uj9qIMcfmH8/s320/abr+report0006.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://3.bp.blogspot.com/-Ts7NqMq4uAw/T4GvoUgsaRI/AAAAAAAAAJg/frziG_H48lQ/s1600/abr+report0007.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="238" src="http://3.bp.blogspot.com/-Ts7NqMq4uAw/T4GvoUgsaRI/AAAAAAAAAJg/frziG_H48lQ/s320/abr+report0007.jpg" width="320" /></a></div><br />
<div class="separator" style="clear: both; text-align: center;"><a href="http://1.bp.blogspot.com/-dLWYg65ytu0/T4GvuT_Q8NI/AAAAAAAAAJo/87gxYz74wog/s1600/abr+report0008.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="263" src="http://1.bp.blogspot.com/-dLWYg65ytu0/T4GvuT_Q8NI/AAAAAAAAAJo/87gxYz74wog/s320/abr+report0008.jpg" width="320" /></a></div>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-21356620432867474502012-04-07T19:17:00.000-07:002012-04-07T19:17:37.676-07:00ABR SEPT 2011 assesment with leonid blyum<div class="separator" style="clear: both; text-align: center;"><a href="http://4.bp.blogspot.com/-lPZqQ-OrHwM/T4D1DCsYZII/AAAAAAAAAGE/GI9AE8B7QuU/s1600/DSC_8835.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="212" src="http://4.bp.blogspot.com/-lPZqQ-OrHwM/T4D1DCsYZII/AAAAAAAAAGE/GI9AE8B7QuU/s320/DSC_8835.JPG" width="320" /></a></div>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-20885900278910227352012-04-07T19:15:00.000-07:002012-04-07T19:15:15.006-07:00ABR sept 2011<div class="separator" style="clear: both; text-align: center;"><a href="http://3.bp.blogspot.com/-eGTpWCLnUFc/T4D0i_j5PWI/AAAAAAAAAF8/nEhPhmEbreE/s1600/misha+with+leonid.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="212" src="http://3.bp.blogspot.com/-eGTpWCLnUFc/T4D0i_j5PWI/AAAAAAAAAF8/nEhPhmEbreE/s320/misha+with+leonid.JPG" width="320" /></a></div>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-70996380627021887522012-03-15T06:59:00.000-07:002012-03-15T06:59:43.077-07:00AmsterdamWe had a good flight from mexico to amsterdam , misha was able to lay down ,although she wanted to sleep a great time of the flight on my lap,she is a big mamas girl.<br />
It is kind of cold here in amsterdam .<br />
Misha is still on mexican time she wants to eat at like 2 am and sleeps a big part of the day<br />
This sunday we will drive to hasselt belgium for our training on monday <br />
We are hopping for very good results lets see and wait .<br />
My little angel is also a sleep like an angel and it is almost 3 pm she needs to wake up!!!!<br />
Lets see what's up with the little senorita.misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-6787431476621510832012-02-27T14:25:00.000-08:002012-02-27T14:25:18.184-08:00going to crit oaxacathis sunday we will drive 6 hours to go for our week of reabilitacion in the CRIT oaxaca <br />
then we will drive back after a very bussy week saterday morning to fly sunday to mexico city and then to amsterdam ,so we will be doing lots of traveling ,hope misha will be ok she does not like to travel to much and special not a fleight of 11 hours ,also in amsterdam it is kind of cold compared to puerto heat <br />
amsterdam it is like 8 to 10 degrees celcius and in puerto it is like 33 degrees celcius ,so kind of a lot.<br />
so we have a lot to do for the next weeks <br />
so for now we are happy to be at home .misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-73892930213728476572012-02-10T09:53:00.001-08:002012-02-10T09:53:31.128-08:00my love<div class="separator" style="clear: both; text-align: center;"><a href="http://2.bp.blogspot.com/-SH33IWwHK9s/TzVZfvoCyoI/AAAAAAAAAFs/nEskaUJHHNQ/s1600/DSC01061.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="240" src="http://2.bp.blogspot.com/-SH33IWwHK9s/TzVZfvoCyoI/AAAAAAAAAFs/nEskaUJHHNQ/s320/DSC01061.JPG" width="320" /></a></div>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-56667982947871224392012-02-10T09:48:00.000-08:002012-02-10T09:48:26.910-08:00from the ABR blog<a href="http://youtu.be/5s6E4_zQ9dw">http://youtu.be/5s6E4_zQ9dw</a><br />
<br />
this is a link to the ABR blog giving a explanacion abouth the ABR theqnicsmisha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-71199614248346439672012-02-07T20:01:00.000-08:002012-02-07T20:01:42.452-08:00going to the CRIT in marchmisha has her next apiontment in the CRIT Oaxaca on 5 of march for a whole week <br />
a friend who got back a week ago gave me a very disturbing news <br />
over the christmass vacation some one broke in to the CRIT and stole all there computers !!!!!!!!<br />
i really do not understand how someone can do that !!!!<br />
they are taking away opertunities of childeren with special needs ,the CRIT gives opertunitys to childeren without finacial facilitys so they can still get the help they desperate need <br />
the CRIT is build on donations ,so the parents pay very little for there reabilitacion and docters what they otherwhise will not be able to getmisha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-53779329751630703122012-02-07T19:43:00.000-08:002012-02-07T19:43:43.241-08:00getting strongersome days misha has lots of reflux and today is one of them ,but i am happy to say i only gave her a bit more of her normal zantac drink and she went to sleep ,she did it her self <br />
normaly i have to give her something very stong to help her sleep but today she did all by her self i am so proud of her this means she is getting stronger yeaaaamisha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-7367760006540440582012-02-05T22:17:00.000-08:002012-02-05T22:17:20.156-08:00G tubeThe other day I read a bouth an other child like misha who is getting a g-tube .<br />
It made me start to think ,I have been told misha is in the 20% of this type of children that can eat normal then I fought that is very good ,lucky little angel.<br />
Then I rememberd that when misha was little no one ever talked to me about that she can have feeding problems ,so it has never been in my mind to limit the way she eats ,I do give her small pieces but she eats solid foods and she chews.<br />
To my personal point of few I think you suld not limit a child then you will create the limitation ,like they always told me do not put misha on her belly have her sitting in a 45% angel this limitations have made to my personal point of few many of misha her limited neck control and sitting possibility ,at one month of age misha was starting with her head control she kept her head up ,they gave her so much ant epileptic medication she slept for almost 6 months ,her drugs where in a very high dose she slept even when eating .misha could not develp any further she was a very strong baby ,by her I feel the limitation that where put on us made also that misha has more disability that she needed to have and she was Olson over medicated , when we got to Rome misha was still on the same dose of medicine as they gave her in her first month and the neurologist said she was on a high dose ,she was double the weight !!!!!!misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-28855513618265674392012-01-19T22:50:00.000-08:002012-01-19T22:50:12.079-08:00misha is getting stronger and that makes me very happy i love to see the changes in her they are small but very big for us ,and it gives us great pleaser to share this with our friends <br />
we are doing as many hours of ABR as we can per day i love to do more but the this week i had to leave a lot so we could not get all the hours we want <br />
misha is also getting more her own will ,she nows more what she wants and when she wants it <br />
before i could work on her till late at night now at night she wants to go to her bed and sleep.<br />
that is good progressmisha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com0tag:blogger.com,1999:blog-1724846699690919685.post-46306515667463584962012-01-17T12:13:00.000-08:002012-01-17T12:13:41.027-08:00misha eating pizza and loving it<div class="separator" style="clear: both; text-align: center;"><br />
</div><div class="separator" style="clear: both; text-align: center;"><iframe allowfullscreen='allowfullscreen' webkitallowfullscreen='webkitallowfullscreen' mozallowfullscreen='mozallowfullscreen' width='320' height='266' src='https://www.blogger.com/video.g?token=AD6v5dxKzcBk1LMT2Ng8Db6B7fIUbv5Hk6UHXcJoK-xP9Ds6dUUZr6GhkhcGrUGrQx2YUICXs0yTavWkiDEu2nqeLQ' class='b-hbp-video b-uploaded' frameborder='0'></iframe></div>misha's journeyhttp://www.blogger.com/profile/00628132175676165808noreply@blogger.com2